Endocrine Abstracts

Multiple sclerosis (MS) is a common inflammatory autoimmune and demyelinating disease of the central nervous system (CNS) that compromises health and leads to disability. Sex differences in the prevalence and progression of MS suggest the involvement of sex steroids in the pathophysiology of MS. In late pregnancy, at the highest levels of progesterone and estradiol, the number of relapses decreases and increases again after delivery due to changes in steroid levels. In additio...